The Enzyme Database

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EC 2.5.1.80     
Accepted name: 7-dimethylallyltryptophan synthase
Reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan
Other name(s): 7-DMATS
Systematic name: dimethylallyl-diphosphate:L-tryptophan 7-dimethylallyltransferase
Comments: This enzyme is more flexible towards the aromatic substrate than EC 2.5.1.34 (4-dimethylallyltryptophan synthase), but similar to that enzyme, accepts only dimethylallyl diphosphate as the prenyl donor.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Kremer, A. and Li, S.M. Potential of a 7-dimethylallyltryptophan synthase as a tool for production of prenylated indole derivatives. Appl. Microbiol. Biotechnol. 79 (2008) 951–961. [PMID: 18481055]
2.  Kremer, A., Westrich, L. and Li, S.M. A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization. Microbiology 153 (2007) 3409–3416. [PMID: 17906140]
[EC 2.5.1.80 created 2010]
 
 


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