The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 2.5.1.65     
Accepted name: O-phosphoserine sulfhydrylase
Reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate
Other name(s): O-phosphoserine(thiol)-lyase
Systematic name: O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
Comments: A pyridoxal-phosphate protein. The enzyme from Aeropyrum pernix acts on both O-phospho-L-serine and O3-acetyl-L-serine, in contrast with EC 2.5.1.47, cysteine synthase, which acts only on O3-acetyl-L-serine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 1071505-11-7
References:
1.  Mino, K. and Ishikawa, K. A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1. FEBS Lett. 551 (2003) 133–138. [PMID: 12965218]
2.  Mino, K. and Ishikawa, K. Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1. J. Bacteriol. 185 (2003) 2277–2284. [PMID: 12644499]
3.  Mino, K. and Ishikawa, K. Crystallization and preliminary X-ray diffraction analysis of O-acetylserine sulfhydrylase from Aeropyrum pernix K1. Acta Crystallogr. D Biol. Crystallogr. 59 (2003) 338–340. [PMID: 12554945]
[EC 2.5.1.65 created 2004]
 
 


Data © 2001–2016 IUBMB
Web site © 2005–2016 Andrew McDonald