| EC |
2.5.1.155 |
| Accepted name: |
phosphoglycerol geranylfarnesyltransferase |
| Reaction: |
all-trans-pentaprenyl diphosphate + sn-glycerol 1-phosphate = sn-3-O-(farnesylgeranyl)glycerol 1-phosphate + diphosphate |
| Other name(s): |
GFGP synthase |
| Systematic name: |
all-trans pentaprenyl diphosphate:sn-glycerol-1-phosphate pentaprenyltransferase |
| Comments: |
The enzyme, characterized from the archaeon Aeropyrum pernix, catalyses the first pathway-specific step in the biosynthesis of the core membrane C25,C25-diether lipids in some archaea. It does not act on geranylgeranyl diphosphate. cf. EC 2.5.1.41, phosphoglycerol geranylgeranyltransferase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Yoshida, R., Yoshimura, T. and Hemmi, H. Biosynthetic machinery for C25,C25-diether archaeal lipids from the hyperthermophilic archaeon Aeropyrum pernix. Biochem. Biophys. Res. Commun. 497 (2018) 87–92. [DOI] [PMID: 29427665] |
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| [EC 2.5.1.155 created 2022] |
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