| EC |
2.4.1.122 |
| Accepted name: |
glycoprotein-N-acetylgalactosamine 3-β-galactosyltransferase |
| Reaction: |
UDP-galactose + glycoprotein N-acetyl-D-galactosamine = UDP + glycoprotein D-galactosyl-(1→3)-N-acetyl-D-galactosamine |
| Other name(s): |
uridine diphosphogalactose-mucin β-(1→3)-galactosyltransferase |
| Systematic name: |
UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-β-D-galactosyltransferase |
| Comments: |
The non-reducing O-serine-linked N-acetylgalactosamine residues in mucin glycoproteins can act as acceptors. |
| Links to other databases: |
BRENDA, EXPASY, IUBMB, KEGG, CAS registry number: 97089-61-7 |
| References: |
| 1. |
Hesford, F.J., Berger, E.G. and van den Eijnden, D.H. Identification of the product formed by human erythrocyte galactosyltransferase. Biochim. Biophys. Acta 659 (1981) 302–311. [PMID: 6789880] |
| 2. |
Mendicino, J., Sivakami, S., Davila, M. and Chandrasekaran, E.V. Purification and properties of UDP-gal:N-acetylgalactosaminide mucin: β1,3-galactosyltransferase from swine trachea mucosa. J. Biol. Chem. 257 (1982) 3987–3994. [PMID: 6801057] |
| 3. |
Schachter, H., Narasimhan, S., Gleeson, P. and Vella, G. Glycosyltransferases involved in elongation of N-glycosidically linked oligosaccharides of the complex or N-acetyllactosamine type. Methods Enzymol. 98 (1983) 98–134. [PMID: 6366476] |
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| [EC 2.4.1.122 created 1984] |
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