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Your query returned 1 entry. Printable version
EC | 2.4.1.109 | ||||
Accepted name: | dolichyl-phosphate-mannose—protein mannosyltransferase | ||||
Reaction: | (1) dolichyl β-D-mannosyl phosphate + L-threonyl-[protein] = dolichyl phosphate + 3-O-(α-D-mannosyl)-L-threonyl-[protein] (2) dolichyl β-D-mannosyl phosphate + L-seryl-[protein] = dolichyl phosphate + 3-O-(α-D-mannosyl)-L-seryl-[protein] |
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For diagram of glycoprotein biosynthesis, click here | |||||
Other name(s): | dolichol phosphomannose-protein mannosyltransferase; protein O-D-mannosyltransferase; dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase; dolichyl-phosphate-mannose-protein mannosyltransferase; dolichyl-D-mannosyl-phosphate:protein O-D-mannosyltransferase | ||||
Systematic name: | dolichyl β-D-mannosyl-phosphate:L-threonyl/L-seryl-[protein] O-D-mannosyltransferase (configuration-inverting) | ||||
Comments: | The enzyme transfers mannosyl residues to the hydroxy group of serine or threonine residues, producing cell-wall mannoproteins. It acts only on long-chain α-dihydropolyprenyl derivatives, larger than C35. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 74315-99-4 | ||||
References: |
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