The Enzyme Database

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EC 2.3.2.28     
Accepted name: L-allo-isoleucyltransferase
Reaction: L-allo-isoleucyl-S-[CmaA peptidyl-carrier protein] + holo-[CmaD peptidyl-carrier protein] = L-allo-isoleucyl-S-[CmaD peptidyl-carrier protein] + holo-[CmaA peptidyl-carrier protein]
Glossary: L-allo-isoleucine = (2S,3R)-2-amino-3-methylpentanoic acid
Other name(s): CmaE
Systematic name: L-allo-isoleucyl-S-[CmaA peptidyl-carrier protein]:holo-[CmaD peptidyl-carrier protein] L-allo-isoleucyltransferase
Comments: The enzyme, characterized from the bacterium Pseudomonas syringae, is involved in the biosynthesis of the toxin coronatine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Vaillancourt, F.H., Yeh, E., Vosburg, D.A., O'Connor, S.E. and Walsh, C.T. Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis. Nature 436 (2005) 1191–1194. [PMID: 16121186]
2.  Strieter, E.R., Vaillancourt, F.H. and Walsh, C.T. CmaE: a transferase shuttling aminoacyl groups between carrier protein domains in the coronamic acid biosynthetic pathway. Biochemistry 46 (2007) 7549–7557. [PMID: 17530782]
[EC 2.3.2.28 created 2015]
 
 


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