| EC |
2.3.1.74 |
| Accepted name: |
naringenin-chalcone synthase |
| Reaction: |
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2 |
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For diagram of chalcone and stilbene biosynthesis, click here |
| Other name(s): |
chalcone synthase; flavanone synthase; 6′-deoxychalcone synthase; chalcone synthetase; DOCS; CHS |
| Systematic name: |
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing) |
| Comments: |
In the presence of NADH and a reductase, 6′-deoxychalcone is produced. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, PDB, CAS registry number: 56803-04-4 |
| References: |
| 1. |
Ayabe, S.-I., Udagawa, A. and Furuya, T. NAD(P)H-dependent 6′-deoxychalcone synthase activity in Glycyrrhiza echinata cells induced by yeast extract. Arch. Biochem. Biophys. 261 (1988) 458–462. [PMID: 3355160] |
| 2. |
Heller, W. and Hahlbrock, K. Highly purified "flavanone synthase" from parsley catalyzes the formation of naringenin chalcone. Arch. Biochem. Biophys. 200 (1980) 617–619. [PMID: 7436427] |
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| [EC 2.3.1.74 created 1984] |
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