| EC |
2.3.1.280 |
| Accepted name: |
(aminoalkyl)phosphonate N-acetyltransferase |
| Reaction: |
acetyl-CoA + (aminomethyl)phosphonate = CoA + (acetamidomethyl)phosphonate |
| Other name(s): |
phnO (gene name) |
| Systematic name: |
acetyl-CoA:(aminomethyl)phosphonate N-acetyltransferase |
| Comments: |
The enzyme, characterized from the bacterium Escherichia coli, is able to acetylate a range of (aminoalkyl)phosphonic acids. Requires a divalent metal ion for activity. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Errey, J.C. and Blanchard, J.S. Functional annotation and kinetic characterization of PhnO from Salmonella enterica. Biochemistry 45 (2006) 3033–3039. [PMID: 16503658] |
| 2. |
Hove-Jensen, B., McSorley, F.R. and Zechel, D.L. Catabolism and detoxification of 1-aminoalkylphosphonic acids: N-acetylation by the phnO gene product. PLoS One 7:e46416 (2012). [PMID: 23056305] |
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| [EC 2.3.1.280 created 2018] |
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