The Enzyme Database

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EC 2.1.3.7     
Accepted name: 3-hydroxymethylcephem carbamoyltransferase
Reaction: carbamoyl phosphate + a 3-hydroxymethylceph-3-em-4-carboxylate = phosphate + a 3-carbamoyloxymethylcephem
Systematic name: carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase
Comments: Acts on a wide range of 3-hydroxymethylcephems (a subclass of the cephalosporin antibiotics). Activated by ATP.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 74315-96-1
References:
1.  Brewer, S.J., Taylor, P.M. and Turner, M.K. An adenosine triphosphate-dependent carbamoylphosphate--3-hydroxymethylcephem O-carbamoyltransferase from Streptomyces clavuligerus. Biochem. J. 185 (1980) 555–564. [PMID: 6248024]
[EC 2.1.3.7 created 1983]
 
 


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