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Accepted name: cyclopropane-fatty-acyl-phospholipid synthase
S-adenosyl- L-methionine + phospholipid olefinic fatty acid = S-adenosyl- L-homocysteine + phospholipid cyclopropane fatty acid
Other name(s): cyclopropane synthetase; unsaturated-phospholipid methyltransferase; cyclopropane synthase; cyclopropane fatty acid synthase; cyclopropane fatty acid synthetase; CFA synthase
S-adenosyl- L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)
Comments: The enzyme adds a methylene group across the 9,10 position of a Δ
-olefinic acyl chain in phosphatidylethanolamine or, more slowly, phosphatidylglycerol or phosphatidylinositol, forming a cyclopropane derivative ( 9 cf. EC 220.127.116.11 methylene-fatty-acyl-phospholipid synthase).
Links to other databases:
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 51845-48-8
Chung, A.E. and Law, J.H. Cyclopropane fatty acid synthetase: Partial purification and properties.
Biochemistry 3 (1964) 967–974. [PMID: 14214089]
Zalkin, H., Law, J.H. and Goldfine, H. Enzymatic synthesis of cyclopropane fatty acids catalyzed by bacterial extracts.
J. Biol. Chem. 238 (1963) 1242–1248. [PMID: 14003136]
[EC 18.104.22.168 created 1986]
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