The Enzyme Database

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Accepted name: 25S rRNA (cytosine2870-C5)-methyltransferase
Reaction: S-adenosyl-L-methionine + cytosine2870 in 25S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine2870 in 25S rRNA
Other name(s): NOP2 (gene name)
Systematic name: S-adenosyl-L-methionine:25S rRNA (cytosine2870-C5)-methyltransferase
Comments: The enzyme, found in eukaryotes, is specific for cytosine2870 of the 25S ribosomal RNA. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae [1].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Sharma, S., Yang, J., Watzinger, P., Kotter, P. and Entian, K.D. Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively. Nucleic Acids Res. 41 (2013) 9062–9076. [PMID: 23913415]
[EC created 2014]

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