5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin = a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin
cdhD (gene name); cdhE (gene name)
5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein methyltransferase
Catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin. Forms, together with EC 220.127.116.11, carbon-monoxide dehydrogenase (ferredoxin) and EC 18.104.22.168, CO-methylating acetyl-CoA synthase, the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2. This reaction is a key step in methanogenesis from acetate.
Maupin-Furlow, J. and Ferry, J.G. Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila. J. Bacteriol.178 (1996) 340–346. [PMID: 8550451]
Grahame, D.A. and DeMoll, E. Partial reactions catalyzed by protein components of the acetyl-CoA decarbonylase synthase enzyme complex from Methanosarcina barkeri. J. Biol. Chem.271 (1996) 8352–8358. [PMID: 8626532]