The Enzyme Database

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EC 2.1.1.140     
Accepted name: (S)-coclaurine-N-methyltransferase
Reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine
For diagram of reticuline-biosynthesis pathway, click here
Systematic name: S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase
Comments: The enzyme is specific for the (S)-isomer of coclaurine. Norcoclaurine can also act as an acceptor.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 167398-06-3
References:
1.  Loeffler, S., Deus-Neumann, B. and Zenk, M.H. S-Adenosyl-L-methionine: (S)-coclaurine-N-methyltransferase from Tinospora cordifolia. Phytochemistry 38 (1995) 1387–1395.
[EC 2.1.1.140 created 2001]
 
 


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