The Enzyme Database

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EC 2.1.1.122     
Accepted name: (S)-tetrahydroprotoberberine N-methyltransferase
Reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine
For diagram of stylopine biosynthesis, click here and for diagram of canadine biosynthesis, click here
Other name(s): tetrahydroprotoberberine cis-N-methyltransferase
Systematic name: S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase
Comments: Involved in the biosynthesis of isoquinoline alkaloids in plants.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 106878-42-6
References:
1.  Rueffer, M., Zumstein, G., Zenk, M.H. Partial purification and characterization of S-adenosyl-L-methionine:(S)-tetrahydroprotoberberine cis-N-methyltransferase from suspension-cultured cells of Eschscholtzia and Corydalis. Phytochemistry 29 (1990) 3727–3733.
[EC 2.1.1.122 created 1999]
 
 


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