The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.3.7.4     
Accepted name: phytochromobilin:ferredoxin oxidoreductase
Reaction: (3Z)-phytochromobilin + 2 oxidized ferredoxin = biliverdin IXα + 2 reduced ferredoxin
For diagram of biliverdin metabolism, click here
Other name(s): HY2; PPhi B synthase; phytochromobilin synthase
Systematic name: (3Z)-phytochromobilin:ferredoxin oxidoreductase
Comments: Catalyses the two-electron reduction of biliverdin IXα. Can use [2Fe-2S] ferredoxins from a number of sources as acceptor but not the [4Fe-4S] ferredoxin from Clostridium pasteurianum. The isomerization of (3Z)-phytochromobilin to (3E)-phytochromobilin is thought to occur prior to covalent attachment to apophytochrome in the plant cell cytoplasm. Flavodoxins can be used instead of ferredoxin.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 138263-99-7
References:
1.  Frankenberg, N., Mukougawa, K., Kohchi, T. and Lagarias, J.C. Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms. Plant Cell 13 (2001) 965–978. [PMID: 11283349]
2.  McDowell, M.T. and Lagarias, J.C. Purification and biochemical properties of phytochromobilin synthase from etiolated oat seedlings. Plant Physiol. 126 (2001) 1546–1554. [PMID: 11500553]
3.  Terry, M.J., Wahleithner, J.A. and Lagarias, J.C. Biosynthesis of the plant photoreceptor phytochrome. Arch. Biochem. Biophys. 306 (1993) 1–15. [DOI] [PMID: 8215388]
[EC 1.3.7.4 created 2002]
 
 


Data © 2001–2019 IUBMB
Web site © 2005–2019 Andrew McDonald