The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.3.1.45     
Accepted name: 2′-hydroxyisoflavone reductase
Reaction: vestitone + NADP+ = 2′-hydroxyformononetin + NADPH + H+
For diagram of the biosynthesis of formononetin and derivatives, click here
Other name(s): NADPH:2′-hydroxyisoflavone oxidoreductase; isoflavone reductase; 2′,7-dihydroxy-4′,5′-methylenedioxyisoflavone reductase
Systematic name: vestitone:NADP+ oxidoreductase
Comments: In the reverse reaction, a 2′-hydroxyisoflavone is reduced to an isoflavanone; 2′-hydroxypseudobaptigenin also acts. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 128449-69-4
References:
1.  Tiemann, K., Hinderer, W. and Barz, W. Isolation of NADPH:isoflavone oxidoreductase, a new enzyme of pterocarpan biosynthesis in cell suspensions of Cicer arietinum. FEBS Lett. 213 (1987) 324–328.
[EC 1.3.1.45 created 1990]
 
 


Data © 2001–2016 IUBMB
Web site © 2005–2016 Andrew McDonald