| EC |
1.2.1.69 |
| Accepted name: |
fluoroacetaldehyde dehydrogenase |
| Reaction: |
fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+ |
| Systematic name: |
fluoroacetaldehyde:NAD+ oxidoreductase |
| Comments: |
The enzyme from Streptomyces cattleya has a high affinity for fluoroacetate and glycolaldehyde but not for acetaldehyde. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 387336-50-7 |
| References: |
| 1. |
Murphy, C.D., Moss, S.J. and O'Hagan, D. Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya. Appl. Environ. Microbiol. 67 (2001) 4919–4921. [DOI] [PMID: 11571203] |
| 2. |
Murphy, C.D., Schaffrath, C. and O'Hagan, D. Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. Chemosphere 52 (2003) 455–461. [DOI] [PMID: 12738270] |
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| [EC 1.2.1.69 created 2003] |
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