The Enzyme Database

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EC 1.2.1.44     
Accepted name: cinnamoyl-CoA reductase
Reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+
Other name(s): feruloyl-CoA reductase; cinnamoyl-coenzyme A reductase; ferulyl-CoA reductase; feruloyl coenzyme A reductase; p-hydroxycinnamoyl coenzyme A reductase; cinnamoyl-CoA:NADPH reductase
Systematic name: cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)
Comments: Acts also on a number of substituted cinnamoyl esters of coenzyme A.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 59929-39-4
References:
1.  Gross, G.G. and Kreiten, W. Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia. FEBS Lett. 54 (1975) 259–262. [PMID: 236926]
2.  Sarni, F., Grand, C. and Baudet, A.M. Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana). Eur. J. Biochem. 139 (1984) 259–265. [PMID: 6365550]
3.  Wengenmayer, H., Ebel, J. and Grisebach, H. Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax). Eur. J. Biochem. 65 (1976) 529–536. [PMID: 7454]
[EC 1.2.1.44 created 1978]
 
 


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