The Enzyme Database

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EC 1.2.1.16     
Accepted name: succinate-semialdehyde dehydrogenase [NAD(P)+]
Reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + 2 H+
For diagram of the citric acid cycle, click here
Other name(s): succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate)); succinate-semialdehyde dehydrogenase [NAD(P)]
Systematic name: succinate-semialdehyde:NAD(P)+ oxidoreductase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, UM-BBD, CAS registry number: 37250-88-7
References:
1.  Jakoby, W.B. Aldehyde dehydrogenases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds), The Enzymes, 2nd edn, vol. 7, Academic Press, New York, 1963, pp. 203–221.
2.  Jakoby, W.B. and Scott, E.M. Aldehyde oxidation. III. Succinic semialdehyde dehydrogenase. J. Biol. Chem. 234 (1959) 937–940. [PMID: 13654295]
3.  Nirenberg, M.W. and Jakoby, W.B. Enzymatic utilization of γ-hydroxybutyric acid. J. Biol. Chem. 235 (1960) 954–960. [PMID: 14427301]
[EC 1.2.1.16 created 1965]
 
 


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