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Your query returned 1 entry. Printable version
EC | 1.14.14.50 | ||
Accepted name: | tabersonine 3-oxygenase | ||
Reaction: | (1) 16-methoxytabersonine + [reduced NADPH—hemoprotein reductase] + O2 = (3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH—hemoprotein reductase] + H2O (2) tabersonine + [reduced NADPH—hemoprotein reductase] + O2 = (3R)-3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH—hemoprotein reductase] + H2O |
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For diagram of vindoline biosynthesis, click here | |||
Other name(s): | T3O; CYP71D1V2 | ||
Systematic name: | 16-methoxytabersonine,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating) | ||
Comments: | This cytochrome P-450 (heme thiolate) enzyme acts on 16-methoxytabersonine, leading to biosynthesis of vindoline in the plant Catharanthus roseus (Madagascar periwinkle). It can also act on tabersonine, resulting in the production of small amounts of vindorosine. The products are unstable and, in the absence of EC 1.1.99.41, 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase, will convert into 3-epoxylated compounds. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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