| EC |
1.13.12.4 |
| Accepted name: |
lactate 2-monooxygenase |
| Reaction: |
(S)-lactate + O2 = acetate + CO2 + H2O |
| Other name(s): |
lactate oxidative decarboxylase; lactate oxidase; lactic oxygenase; lactate oxygenase; lactic oxidase; L-lactate monooxygenase; lactate monooxygenase; L-lactate-2-monooxygenase |
| Systematic name: |
(S)-lactate:oxygen 2-oxidoreductase (decarboxylating) |
| Comments: |
A flavoprotein (FMN). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, CAS registry number: 9028-72-2 |
| References: |
| 1. |
Hayaishi, O. and Sutton, W.B. Enzymatic oxygen fixation into acetate concomitant with the enzymatic decarboxylation of L-lactate. J. Am. Chem. Soc. 79 (1957) 4809–4810. |
| 2. |
Sutton, W.B. Mechanism of action and crystalization of lactic oxidative decarboxylase from Mycobacterium phlei. J. Biol. Chem. 226 (1957) 395–405. [PMID: 13428772] |
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| [EC 1.13.12.4 created 1961 as EC 1.1.3.2, transferred 1972 to EC 1.13.12.4] |
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