ExplorEnz: EC 1.1.3.40

Your query returned 1 entry. Printable version

1.1.3.40

Accepted name:

D-mannitol oxidase

Reaction:

D-mannitol + O₂ = D-mannose + H₂O₂

Other name(s):

mannitol oxidase; D-arabitol oxidase

Systematic name:

mannitol:oxygen oxidoreductase (cyclizing)

Comments:

Also catalyses the oxidation of D-arabinitol and, to a lesser extent, D-glucitol (sorbitol), whereas L-arabinitol is not a good substrate. The enzyme from the snails Helix aspersa and Arion ater is found in a specialised tubular organelle that has been termed the mannosome.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 73562-29-5

References:

1.	Vorhaben, J.E., Scott, J.F., Smith, D.D. and Campbell, J.W. Mannitol oxidase: partial purification and characterisation of the membrane-bound enzyme from the snail Helix aspersa. Int. J. Biochem. 18 (1986) 337–344. [PMID: 3519307]
2.	Malik, Z., Jones, C.J.P. and Connock, M.J. Assay and subcellular localization of H₂O₂ generating mannitol oxidase in the terrestrial slug Arion ater. J. Exp. Zool. 242 (1987) 9–15.
3.	Large, A.T., Jones, C.J.P. and Connock, M.J. The association of mannitol oxidase with a distinct organelle in the digestive gland of the terrestrial slug Arion ater. Protoplasma 175 (1993) 93–101.
4.	Lobo-da-Cunha, A., Amaral-de-Carvalho, D., Oliveira, E., Alves, A., Costa, V. and Calado, G. Mannitol oxidase and polyol dehydrogenases in the digestive gland of gastropods: Correlations with phylogeny and diet. PLoS One 13:e0193078 (2018). [PMID: 29529078]

[EC 1.1.3.40 created 2001]