EC |
1.1.1.404 |
Accepted name: |
tetrachlorobenzoquinone reductase |
Reaction: |
2,3,5,6-tetrachlorohydroquinone + NAD+ = 2,3,5,6-tetrachloro-1,4-benzoquinone + NADH + H+ |
Other name(s): |
pcpD (gene name); TCBQ reductase |
Systematic name: |
2,3,5,6-tetrachlorohydroquinone:NAD+ oxidoreductase |
Comments: |
Contains FMN. The enzyme, characterized from the bacterium Sphingobium chlorophenolicum, participates in the degradation of pentachlorophenol. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Chen, L. and Yang, J. Biochemical characterization of the tetrachlorobenzoquinone reductase involved in the biodegradation of pentachlorophenol. Int. J. Mol. Sci. 9 (2008) 198–212. [PMID: 19325743] |
2. |
Yadid, I., Rudolph, J., Hlouchova, K. and Copley, S.D. Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol. Proc. Natl. Acad. Sci. USA 110 (2013) E2182–E2190. [DOI] [PMID: 23676275] |
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[EC 1.1.1.404 created 2017] |
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