EC |
1.1.1.370 |
Accepted name: |
scyllo-inositol 2-dehydrogenase (NAD+) |
Reaction: |
scyllo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+ |
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For diagram of inositol catabolism, click here |
Glossary: |
2,4,6/3,5-pentahydroxycyclohexanone = (2R,3S,4s,5R,6S)-2,3,4,5,6-pentahydroxycyclohexanone = scyllo-inosose |
Other name(s): |
iolX (gene name) |
Systematic name: |
scyllo-inositol:NAD+ 2-oxidoreductase |
Comments: |
The enzyme, found in the bacterium Bacillus subtilis, has no activity with NADP+ [cf. EC 1.1.1.371, scyllo-inositol 2-dehydrogenase (NADP+)]. It is part of a scyllo-inositol degradation pathway leading to acetyl-CoA. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Morinaga, T., Ashida, H. and Yoshida, K. Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis. Microbiology 156 (2010) 1538–1546. [DOI] [PMID: 20133360] |
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[EC 1.1.1.370 created 2014] |
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