The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.1.1.21     
Accepted name: aldehyde reductase
Reaction: alditol + NAD(P)+ = aldose + NAD(P)H + H+
Other name(s): aldose reductase; polyol dehydrogenase (NADP+); ALR2; alditol:NADP oxidoreductase; alditol:NADP+ 1-oxidoreductase; NADPH-aldopentose reductase; NADPH-aldose reductase
Systematic name: alditol:NAD(P)+ 1-oxidoreductase
Comments: Has wide specificity.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9028-31-3
References:
1.  Attwood, M.A. and Doughty, C.C. Purification and properties of calf liver aldose reductase. Biochim. Biophys. Acta 370 (1974) 358–368. [PMID: 4216364]
2.  Boghosian, R.A. and McGuinness, E.T. Affinity purification and properties of porcine brain aldose reductase. Biochim. Biophys. Acta 567 (1979) 278–286. [PMID: 36151]
3.  Hers, H.G. L’Aldose-réductase. Biochim. Biophys. Acta 37 (1960) 120–126. [PMID: 14401390]
4.  Scher, B.M. and Horecker, B.L. Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis. Arch. Biochem. Biophys. 116 (1966) 117–128. [PMID: 4381350]
[EC 1.1.1.21 created 1961 (EC 1.1.1.139 created 1972, incorporated 1978)]
 
 


Data © 2001–2014 IUBMB
Web site © 2005–2014 Andrew McDonald