| EC |
1.1.1.16 |
| Accepted name: |
galactitol 2-dehydrogenase |
| Reaction: |
galactitol + NAD+ = D-tagatose + NADH + H+ |
| Other name(s): |
dulcitol dehydrogenase; AtuSorbD (gene name); galactitol:NAD+ 2-oxidoreductase |
| Systematic name: |
galactitol:NAD+ 2-oxidoreductase (D-tagatose-forming) |
| Comments: |
Also converts other alditols containing an L-threo-configuration adjacent to a primary alcohol group into the corresponding sugars. The enzyme from Agrobacterium fabrum C58 is part of D-altritol and galactitol degradation pathways. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9028-23-3 |
| References: |
| 1. |
Shaw, D.R.D. Polyol dehydrogenases. 3. Galactitol dehydrogenase and D-iditol dehydrogenase. Biochem. J. 64 (1956) 394–405. [PMID: 13373783] |
| 2. |
Wichelecki, D.J., Vetting, M.W., Chou, L., Al-Obaidi, N., Bouvier, J.T., Almo, S.C. and Gerlt, J.A. ATP-binding cassette (ABC) transport system solute-binding protein-guided identification of novel D-altritol and galactitol catabolic pathways in Agrobacterium tumefaciens C58. J. Biol. Chem. 290 (2015) 28963–28976. [DOI] [PMID: 26472925] |
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| [EC 1.1.1.16 created 1961] |
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