EC |
5.4.99.65 |
Accepted name: |
pre-α-onocerin synthase |
Reaction: |
(3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene = pre-α-onocerin |
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For diagram of α-onocerin biosynthesis, click here |
Glossary: |
pre-α-onocerin = (21S)-21,22-epoxypolypoda-8(26)-13,17-trien-3β-ol |
Other name(s): |
LCC |
Systematic name: |
(3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene mutase (cyclizing, pre-α-onocerin-forming) |
Comments: |
Isolated from the plant Lycopodium clavatum. The enzyme does not act on (3S)-2,3-epoxy-2,3-dihydrosqualene and does not form any α-onocerin. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Araki, T., Saga, Y., Marugami, M., Otaka, J., Araya, H., Saito, K., Yamazaki, M., Suzuki, H. and Kushiro, T. Onocerin biosynthesis requires two highly dedicated triterpene cyclases in a fern Lycopodium clavatum. ChemBioChem 17 (2016) 288–290. [DOI] [PMID: 26663356] |
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[EC 5.4.99.65 created 2017] |
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EC |
5.4.99.66 |
Accepted name: |
α-onocerin synthase |
Reaction: |
pre-α-onocerin = α-onocerin |
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For diagram of α-onocerin biosynthesis, click here |
Glossary: |
α-onocerin = 8,14-secogammacera-8(26),14(27)-diene-3β,21α-diol
pre-α-onocerin = (21S)-21,22-epoxypolypoda-8(26)-13,17-trien-3β-ol |
Other name(s): |
LCD |
Systematic name: |
pre-α-onocerin mutase (cyclizing, α-onocerin-forming) |
Comments: |
Isolated from the plant Lycopodium clavatum. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Araki, T., Saga, Y., Marugami, M., Otaka, J., Araya, H., Saito, K., Yamazaki, M., Suzuki, H. and Kushiro, T. Onocerin biosynthesis requires two highly dedicated triterpene cyclases in a fern Lycopodium clavatum. ChemBioChem 17 (2016) 288–290. [DOI] [PMID: 26663356] |
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[EC 5.4.99.66 created 2017] |
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