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Your query returned 5 entries. Printable version
EC | 1.14.13.133 | ||||||||||||
Transferred entry: | pentalenene oxygenase. Now EC 1.14.15.32, pentalenene oxygenase | ||||||||||||
EC | 1.14.15.32 | ||||||||||||
Accepted name: | pentalenene oxygenase | ||||||||||||
Reaction: | pentalenene + 4 reduced ferredoxin [iron-sulfur] cluster + 4 H+ + 2 O2 = pentalen-13-al + 4 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O (overall reaction) (1a) pentalenene + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = pentalen-13-ol + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O (1b) pentalen-13-ol + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = pentalen-13-al + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O |
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For diagram of humulene-based sequiterpenoid biosynthesis, click here | |||||||||||||
Other name(s): | PtlI | ||||||||||||
Systematic name: | pentalenene,reduced ferredoxin:oxygen 13-oxidoreductase | ||||||||||||
Comments: | A cytochrome P-450 (heme-thiolate) protein found in the bacterium Streptomyces avermitilis. The enzyme is involved in the biosynthesis of pentalenolactone and related antibiotics. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||
References: |
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EC | 4.2.3.7 | ||||||||||||
Accepted name: | pentalenene synthase | ||||||||||||
Reaction: | (2E,6E)-farnesyl diphosphate = pentalenene + diphosphate | ||||||||||||
For diagram of sesquiterpenoid biosynthesis based on humulene, click here | |||||||||||||
Glossary: | pentalenene = (1R,8aR)-1,4,7,7-tetramethyl-1,2,3,3a,5a,6,7,8-octahydrocyclopenta[c]pentalene | ||||||||||||
Other name(s): | pentalenene synthetase | ||||||||||||
Systematic name: | (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming) | ||||||||||||
Comments: | Isolated from Streptomyces avermitilis. The enzyme is involved in the biosynthesis of pentalenolactone and related antibiotics. The 9si hydrogen of farnesyl diphosphate undergoes a 1,2-hydride shift where it becomes the 1α hydrogen of pentalenene. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 90597-46-9 | ||||||||||||
References: |
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EC | 4.2.3.160 | ||||||||||||
Accepted name: | (2S,3R,6S,9S)-(–)-protoillud-7-ene synthase | ||||||||||||
Reaction: | (2E,6E)-farnesyl diphosphate = (2S,3R,6S,9S)-(–)-protoillud-7-ene + diphosphate | ||||||||||||
For diagram of bicyclic and tricyclic sesquiterpenoids derived from humuladienyl cation, click here and for diagram of protoilludene and related sesquiterpenoids, click here | |||||||||||||
Glossary: | (2S,3R,6S,9S)-(–)-protoillud-7-ene = (2aS,4aS,7aS,7bR)-3,6,6,7b-tetramethyl-2,2a,4a,5,6,7,7a,7b-octahydro-1H-cyclobuta[e]indene pentalenene = (3aS,5aS,8aR)-1,4,7,7-tetramethyl-1,2,3,3a,5a,6,7,8-octahydrocyclopenta[c]pentalene |
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Other name(s): | TPS6 (gene name) | ||||||||||||
Systematic name: | (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (2S,3R,6S,9S)-(–)-protoillud-7-ene-forming] | ||||||||||||
Comments: | The enzyme has been described from the slime-mould Dictyostelium discoideum. It is specific for (2E,6E)-farnesyl diphosphate. While the major product is the sequiterpene (2S,3R,6S,9S)-(–)-protoillud-7-ene, traces of pentalenene are also formed. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||
References: |
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EC | 4.6.1.5 | ||||||||||||
Transferred entry: | pentalenene synthase. Now EC 4.2.3.7, pentalenene synthase | ||||||||||||