The Enzyme Database

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EC 7.6.2.7     
Accepted name: ABC-type taurine transporter
Reaction: ATP + H2O + taurine-[taurine-binding protein][side 1] = ADP + phosphate + taurine[side 2] + [taurine-binding protein][side 1]
Other name(s): tauABC (gene names); taurine ABC transporter; taurine-transporting ATPase
Systematic name: ATP phosphohydrolase (ABC-type, taurine-importing)
Comments: An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. Does not undergo phosphorylation during the transport process. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of taurine. In Escherichia coli the enzyme imports a range of sulfonates (including taurine) that can be used as a source of sulfur.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  van der Ploeg, J.R., Weiss, M.A., Saller, E., Nashimoto, H., Saito, N., Kertesz, M.A. and Leisinger, T. Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source. J. Bacteriol. 178 (1996) 5438–5446. [DOI] [PMID: 8808933]
[EC 7.6.2.7 created 2000 as EC 3.6.3.36, transferred 2018 to EC 7.6.2.7]
 
 


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