The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: ABC-type glutathione transporter
Reaction: ATP + H2O + glutathione-[glutathione-binding protein][side 1] = ADP + phosphate + glutathione[side 2] + [glutathione-binding protein][side 1]
Other name(s): glutathione transporting ATPase; glutathione ABC transporter; gsiACD (gene names)
Systematic name: ATP phosphohydrolase (ABC-type,glutathione-importing)
Comments: A prokaryotic ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from the bacterium Escherichia coli is a heterotrimeric complex that interacts with an extracytoplasmic substrate binding protein to mediate the uptake of glutathione.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Suzuki, H., Koyanagi, T., Izuka, S., Onishi, A. and Kumagai, H. The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette. J. Bacteriol. 187 (2005) 5861–5867. [PMID: 16109926]
2.  Moussatova, A., Kandt, C., O'Mara, M.L. and Tieleman, D.P. ATP-binding cassette transporters in Escherichia coli. Biochim. Biophys. Acta 1778 (2008) 1757–1771. [PMID: 18634750]
[EC created 2019]

Data © 2001–2021 IUBMB
Web site © 2005–2021 Andrew McDonald