| EC |
7.2.2.22 |
| Accepted name: |
P-type Mn2+ transporter |
| Reaction: |
ATP + H2O + Mn2+[side 1] = ADP + phosphate + Mn2+[side 2] |
| Other name(s): |
Mn(II)-translocating P-type ATPase; Mn2+-exporting ATPase; P1B-type ATPase (ambiguous); ctpC (gene name) |
| Systematic name: |
ATP phosphohydrolase (P-type, Mn2+-exporting) |
| Comments: |
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme, detected in mycobacteria, is a high affinity slow turnover ATPase exporting Mn2+. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Padilla-Benavides, T., Long, J.E., Raimunda, D., Sassetti, C.M. and Arguello, J.M. A novel P(1B)-type Mn2+-transporting ATPase is required for secreted protein metallation in mycobacteria. J. Biol. Chem. 288 (2013) 11334–11347. [DOI] [PMID: 23482562] |
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| [EC 7.2.2.22 created 2021] |
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