The Enzyme Database

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EC 7.2.2.20     
Accepted name: ABC-type Zn2+ transporter
Reaction: ATP + H2O + Zn2+-[zinc-binding protein][side 1] = ADP + phosphate + Zn2+[side 2] + [zinc-binding protein][side 1]
Other name(s): Zn2+-transporting ATPase; Zn2+ ABC transporter; znuABC (gene names)
Systematic name: ATP phosphohydrolase (ABC-type, Zn2+-importing)
Comments: ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high-affinity import of Zn2+.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Patzer, S.I. and Hantke, K. The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli. Mol. Microbiol. 28 (1998) 1199–1210. [PMID: 9680209]
2.  Hantke, K. Bacterial zinc uptake and regulators. Curr. Opin. Microbiol. 8 (2005) 196–202. [PMID: 15802252]
[EC 7.2.2.20 created 2019]
 
 


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