EC |
7.2.2.20 |
Accepted name: |
ABC-type Zn2+ transporter |
Reaction: |
ATP + H2O + Zn2+-[zinc-binding protein][side 1] = ADP + phosphate + Zn2+[side 2] + [zinc-binding protein][side 1] |
Other name(s): |
Zn2+-transporting ATPase; Zn2+ ABC transporter; znuABC (gene names) |
Systematic name: |
ATP phosphohydrolase (ABC-type, Zn2+-importing) |
Comments: |
ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high-affinity import of Zn2+. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Patzer, S.I. and Hantke, K. The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli. Mol. Microbiol. 28 (1998) 1199–1210. [PMID: 9680209] |
2. |
Hantke, K. Bacterial zinc uptake and regulators. Curr. Opin. Microbiol. 8 (2005) 196–202. [PMID: 15802252] |
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[EC 7.2.2.20 created 2019] |
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