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Your query returned 1 entry. Printable version
EC | 6.2.1.54 | ||||||||
Accepted name: | D-alanine—[D-alanyl-carrier protein] ligase | ||||||||
Reaction: | ATP + D-alanine + holo-[D-alanyl-carrier protein] = AMP + diphosphate + D-alanyl-[D-alanyl-carrier protein] (overall reaction) (1a) ATP + D-alanine = (D-alanyl)adenylate + diphosphate (1b) (D-alanyl)adenylate + holo-[D-alanyl-carrier protein] = AMP + D-alanyl-[D-alanyl-carrier protein] |
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Other name(s): | dltA (gene name); Dcl | ||||||||
Systematic name: | D-alanine:[D-alanyl-carrier protein] ligase | ||||||||
Comments: | The enzyme is involved in the modification of wall teichoic acids, as well as type I and IV lipoteichoic acids, with D-alanine residues. It activates D-alanine using ATP to form a high-energy (D-alanyl)adenylate intermediate and subsequently transfers the alanyl moiety to the covalently-bound phosphopantheinyl cofactor of a D-alanyl-carrier protein (DltC). | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||
References: |
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