The Enzyme Database

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Accepted name: arachidonate—CoA ligase
Reaction: ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA
Glossary: arachidonate = (all-Z)-icosa-5,8,11,14-tetraenoate
Other name(s): arachidonoyl-CoA synthetase
Systematic name: arachidonate:CoA ligase (AMP-forming)
Comments: Not identical with EC long-chain-fatty-acid—CoA ligase. Icosa-8,11,14-trienoate, but not the other long-chain fatty acids, can act in place of arachidonate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 82047-87-8
1.  Wilson, D.B., Prescott, S.M. and Majerus, P.W. Discovery of an arachidonoyl coenzyme A synthetase in human platelets. J. Biol. Chem. 257 (1982) 3510–3515. [PMID: 7061494]
[EC created 1984]

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