EC |
6.2.1.12 |
Accepted name: |
4-coumarate—CoA ligase |
Reaction: |
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA |
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For diagram of chalcone and stilbene biosynthesis, click here |
Glossary: |
4-coumarate = 3-(4-hydroxyphenyl)prop-2-enoate |
Other name(s): |
4-coumaroyl-CoA synthetase; p-coumaroyl CoA ligase; p-coumaryl coenzyme A synthetase; p-coumaryl-CoA synthetase; p-coumaryl-CoA ligase; feruloyl CoA ligase; hydroxycinnamoyl CoA synthetase; 4-coumarate:coenzyme A ligase; caffeolyl coenzyme A synthetase; p-hydroxycinnamoyl coenzyme A synthetase; feruloyl coenzyme A synthetase; sinapoyl coenzyme A synthetase; 4-coumaryl-CoA synthetase; hydroxycinnamate:CoA ligase; p-coumaryl-CoA ligase; p-hydroxycinnamic acid:CoA ligase; 4CL |
Systematic name: |
4-coumarate:CoA ligase (AMP-forming) |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37332-51-7 |
References: |
1. |
Gross, G.G. and Zenk, M.H. Isolation and properties of hydroxycinnamate: CoA ligase from lignifying tissue of Forsythia. Eur. J. Biochem. 42 (1974) 453–459. [DOI] [PMID: 4364250] |
2. |
Lindl, T., Kreuzaler, F. and Hahlbrock, F. Synthesis of p-coumaroyl coenzyme A with a partially purified p-coumarate:CoA ligase from cell suspension cultures of soybean (Glycine max). Biochim. Biophys. Acta 302 (1973) 457–464. [DOI] [PMID: 4699252] |
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[EC 6.2.1.12 created 1976] |
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