The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: adenylate cyclase
Reaction: ATP = 3′,5′-cyclic AMP + diphosphate
Other name(s): adenylylcyclase; adenyl cyclase; 3′,5′-cyclic AMP synthetase; ATP diphosphate-lyase (cyclizing)
Systematic name: ATP diphosphate-lyase (cyclizing; 3′,5′-cyclic-AMP-forming)
Comments: Also acts on dATP to form 3′,5′-cyclic dAMP. Requires pyruvate. Activated by NAD+ in the presence of EC NAD(P)+—arginine ADP-ribosyltransferase.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9012-42-4
1.  Hirata, M. and Hayaishi, O. Adenyl cyclase of Brevibacterium liquefaciens. Biochim. Biophys Acta 149 (1967) 1–11. [DOI] [PMID: 4295782]
[EC created 1972]

Data © 2001–2022 IUBMB
Web site © 2005–2022 Andrew McDonald