ExplorEnz: EC 4.2.3.213

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4.2.3.213

Accepted name:

colleterpenol synthase

Reaction:

all-trans-hexaprenyl diphosphate + H₂O = colleterpenol + diphosphate

For diagram of Non-Squalene triterpenoid biosynthesis, click here

Glossary:

colleterpenol = (2S)-2-[(1R,3E,7E,11E)-4,8,12-trimethylcyclotetradeca-3,7,11-trien-1-yl]undeca-5,9-dien-2-ol

Other name(s):

CgCS

Systematic name:

pentaprenyl-diphosphate diphosphate-lyase [cyclizing, colleterpenol-forming]

Comments:

Isolated from Colletotrichum gloeosporioides, a pathogenic fungus that causes bitter rot in variety of crops.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

Tao, H., Lauterbach, L., Bian, G., Chen, R., Hou, A., Mori, T., Cheng, S., Hu, B., Lu, L., Mu, X., Li, M., Adachi, N., Kawasaki, M., Moriya, T., Senda, T., Wang, X., Deng, Z., Abe, I., Dickschat, J.S. and Liu, T. Discovery of non-squalene triterpenes. Nature 606 (2022) 414–419. [DOI] [PMID: 35650436]

[EC 4.2.3.213 created 2023]