The Enzyme Database

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Accepted name: indoleacetate decarboxylase
Reaction: (1H-indol-3-yl)acetate = skatole + CO2
For diagram of indoleacetic acid biosynthesis, click here
Glossary: (1H-indol-3-yl)acetate = indoleacetate
skatole = 3-methyl-1H-indole
Other name(s): IAD
Systematic name: (1H-indol-3-yl)acetate carboxy-lyase (skatole-forming)
Comments: This glycyl radical enzyme has been isolate from a number of bacterial species. Skatole contributes to the characteristic smell of animal faeces.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Liu, D., Wei, Y., Liu, X., Zhou, Y., Jiang, L., Yin, J., Wang, F., Hu, Y., Nanjaraj Urs, A.N., Liu, Y., Ang, E.L., Zhao, S., Zhao, H. and Zhang, Y. Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole. Nat. Commun. 9:4224 (2018). [PMID: 30310076]
[EC created 2019]

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