ExplorEnz: EC 4.1.1.115

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4.1.1.115

Accepted name:

indoleacetate decarboxylase

Reaction:

(1H-indol-3-yl)acetate = skatole + CO₂

For diagram of indoleacetic acid biosynthesis, click here

Glossary:

(1H-indol-3-yl)acetate = indoleacetate
skatole = 3-methyl-1H-indole

Other name(s):

IAD

Systematic name:

(1H-indol-3-yl)acetate carboxy-lyase (skatole-forming)

Comments:

This glycyl radical enzyme has been isolate from a number of bacterial species. Skatole contributes to the characteristic smell of animal faeces.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Liu, D., Wei, Y., Liu, X., Zhou, Y., Jiang, L., Yin, J., Wang, F., Hu, Y., Nanjaraj Urs, A.N., Liu, Y., Ang, E.L., Zhao, S., Zhao, H. and Zhang, Y. Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole. Nat. Commun. 9:4224 (2018). [PMID: 30310076]

[EC 4.1.1.115 created 2019]