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Your query returned 1 entry. Printable version
EC | 3.8.1.10 | ||||||||||||||||||
Accepted name: | 2-haloacid dehalogenase (configuration-inverting) | ||||||||||||||||||
Reaction: | (1) (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide (2) (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide |
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For diagram of reaction, click here | |||||||||||||||||||
Other name(s): | 2-haloalkanoic acid dehalogenase; 2-haloalkanoid acid halidohydrolase; DL-2-haloacid dehalogenase; DL-2-haloacid dehalogenase (inversion of configuration); DL-2-haloacid halidohydrolase (inversion of configuration); DL-DEXi; (R,S)-2-haloacid dehalogenase (configuration-inverting) | ||||||||||||||||||
Systematic name: | (S)-2-haloacid dehalogenase (configuration-inverting) | ||||||||||||||||||
Comments: | Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with inversion of configuration at C-2. The enzyme from Pseudomonas sp. 113 acts on 2-haloalkanoic acids whose carbon chain lengths are five or less. [See also EC 3.8.1.2 (S)-2-haloacid dehalogenase, EC 3.8.1.9 (R)-2-haloacid dehalogenase and EC 3.8.1.11 2-haloacid dehalogenase (configuration-retaining)] | ||||||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||||||||
References: |
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