| EC |
3.5.99.15 |
| Accepted name: |
deacetylisoipecoside synthase |
| Reaction: |
deacetylisoipecoside + H2O = dopamine + secologanin |
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For diagram of indole and ipecac alkaloid biosynthesis, click here |
| Glossary: |
dopamine = 4-(2-aminoethyl)benzene-1,2-diol |
| Other name(s): |
deacetylisoipecoside dopamine-lyase; deacetylisoipecoside dopamine-lyase (secologanin-forming) |
| Systematic name: |
deacetylisoipecoside dopamine-hydolase (secologanin-forming) |
| Comments: |
The enzyme from the leaves of Alangium lamarckii differs in enantiomeric specificity from EC 3.5.99.16, deacetylipecoside synthase. The product is rapidly converted to demethylisoalangiside. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 192827-94-4 |
| References: |
| 1. |
DeEknamkul, W., Ounaroon, A., Tanahashi, T., Kutchan, T. and Zenk, M.H. Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii. Phytochemistry 45 (1997) 477–484. [DOI] |
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| [EC 3.5.99.15 created 2000 as EC 4.3.3.3, transferred 2024 to EC 3.5.99.15] |
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