| EC |
3.5.1.9 |
| Accepted name: |
arylformamidase |
| Reaction: |
N-formyl-L-kynurenine + H2O = formate + L-kynurenine |
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For diagram of tryptophan catabolism, click here |
| Other name(s): |
kynurenine formamidase; formylase; formylkynureninase; formylkynurenine formamidase; formamidase I; formamidase II |
| Systematic name: |
aryl-formylamine amidohydrolase |
| Comments: |
Also acts on other aromatic formylamines. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 156229-75-3 |
| References: |
| 1. |
Hayaishi, O. and Stanier, R.Y. The bacterial oxidation of tryptophan. III. Enzymatic activities of cell-free extracts from bacteria employing the aromatic pathway. J. Bacteriol. 62 (1951) 691–709. [PMID: 14907621] |
| 2. |
Jakoby, W.B. Kynurenine formamidase from Neurospora. J. Biol. Chem. 207 (1954) 657–663. [PMID: 13163050] |
| 3. |
Mehler, A.H. and Knox, W.E. The conversion of tryptophan to kynurenine in liver. II. The enzymatic hydrolysis of formylkynurenine. J. Biol. Chem. 187 (1950) 431–438. [PMID: 14794728] |
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| [EC 3.5.1.9 created 1961] |
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