EC |
3.4.24.54 |
Accepted name: |
mucrolysin |
Reaction: |
Cleavage of Ser9┼His, His10┼Leu, Ala14┼Leu, Leu15┼Tyr and Tyr16┼Leu bonds in insulin B chain |
Other name(s): |
Trimeresurus metalloendopeptidase A; mucrotoxin A |
Comments: |
A 94 kDa hemorrhagic and fibrinogenolytic endopeptidase from the Chinese habu snake (Trimeresurus mucrosquamatus) venom. In peptidase family M12 (astacin family) |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 85898-38-0 |
References: |
1. |
Sugihara, H., Moriura, M. and Nikai, T. Purification and properties of a lethal, hemorrhagic protein, "mucrotoxin A", from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus). Toxicon 21 (1983) 247–255. [DOI] [PMID: 6857709] |
2. |
Kishida, M., Nikai, T., Mori, N., Kohmura, S. and Sugihara, H. Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake). Toxicon 23 (1985) 637–645. [PMID: 3904081] |
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[EC 3.4.24.54 created 1992] |
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