The Enzyme Database

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Accepted name: ophiolysin
Reaction: Cleavage of Asn3┼Gln, Gln4┼His, His10┼Leu, Ala14┼Leu, and Tyr16┼Leu in insulin B chain
Other name(s): Ophiophagus metalloendopeptidase
Comments: A 70 kDa endopeptidase from the venom of the king cobra (Ophiophagus hannah)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Yamakawa, Y. and Omori-Satoh, T. A protease in the venom of king cobra (Ophiophagus hannah): purification, characterization and substrate specificity on oxidized insulin B-chain. Toxicon 26 (1988) 1145–1155. [PMID: 3070833]
[EC created 1992]

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