| EC |
3.4.21.2 |
| Accepted name: |
chymotrypsin C |
| Reaction: |
Preferential cleavage: Leu┼, Tyr┼, Phe┼, Met┼, Trp┼, Gln┼, Asn┼ |
| Comments: |
Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family) |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 9036-09-3 |
| References: |
| 1. |
Peanasky, R.J., Gratecos, D., Baratti, J. and Rovery, M. Mode of activation and N-terminal sequence of subunit II in bovine procarboxypeptidase A and of porcine chymotrypsinogen C. Biochim. Biophys. Acta 181 (1969) 82–92. [DOI] [PMID: 5792601] |
| 2. |
Folk, J.E. Chymotrypsin C (porcine pancreas). Methods Enzymol. 19 (1970) 109–112. |
| 3. |
Wilcox, P.E. Chymotrypsinogens - chymotrypsins. Methods Enzymol. 19 (1970) 64–108. |
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| [EC 3.4.21.2 created 1972] |
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