| EC |
3.4.13.20 |
| Accepted name: |
β-Ala-His dipeptidase |
| Reaction: |
Preferential hydrolysis of the β-Ala┼His dipeptide (carnosine), and also anserine, Xaa┼His dipeptides and other dipeptides including homocarnosine |
| Other name(s): |
serum carnosinase |
| Comments: |
Present in the serum of humans and higher primates, but not in the serum of other mammals. Activated by Cd2+ and citrate. Belongs in peptidase family M20. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 525589-43-9 |
| References: |
| 1. |
Lenney, J.F., George, R.P., Weiss, A.M., Kucera, C.M., Chan, P.W.H. and Rinzler, G.S. Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium. Clin. Chim. Acta 123 (1982) 221–231. [DOI] [PMID: 7116644] |
| 2. |
Jackson, M.C., Kucera, C.M. and Lenney, J.F. Purification and properties of human serum carnosinase. Clin. Chim. Acta 196 (1991) 193–206. [DOI] [PMID: 1903095] |
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| [EC 3.4.13.20 created 1992] |
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