| EC |
3.2.2.25 |
| Accepted name: |
N-methyl nucleosidase |
| Reaction: |
7-methylxanthosine + H2O = 7-methylxanthine + D-ribose |
|
For diagram of caffeine biosynthesis, click here |
| Other name(s): |
7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase |
| Systematic name: |
7-methylxanthosine ribohydrolase |
| Comments: |
The enzyme preferentially hydrolyses 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine. Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine-biosynthesis pathway. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Negishi, O., Ozawa, T. and Imagawa, H. N-Methyl nucleosidase from tea leaves. Agric. Biol. Chem. 52 (1988) 169–175. |
|
| [EC 3.2.2.25 created 2007] |
| |
|
| |
|
Printable version