The Enzyme Database

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Accepted name: glycyrrhizin hydrolase
Reaction: glycyrrhizin + H2O = β-D-glucuronosyl-(1→2)-D-glucuronate + glycyrrhetinate
Glossary: glycyrrhizin = glycyrrhizinate
glycyrrhetinate = 3-β-glycyrrhetinate = 3β-hydroxy-11-oxoolean-12-en-30-oate
Other name(s): glycyrrhizinate β-glucuronidase; glycyrrhizin β-hydrolase; glycyrrhizinic acid hydrolase
Systematic name: glycyrrhizinate glucuronosylhydrolase
Comments: The enzyme from Aspergillus niger is specific for the hydrolysis of the triterpenoid glycoside glycyrrhizin from roots of Glycyrrhiza sp.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 102484-56-0
1.  Muro, T., Kuramoto, T., Imoto, K. and Okada, S. Purification and some properties of glycyrrhizinic acid hydrolase from Aspergillus niger GRM3. Agric. Biol. Chem. 50 (1986) 687–692.
[EC created 1989]

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