| EC |
3.1.6.2 |
| Accepted name: |
steryl-sulfatase |
| Reaction: |
3β-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3β-hydroxyandrost-5-en-17-one + sulfate |
| Other name(s): |
arylsulfatase; steroid sulfatase; sterol sulfatase; dehydroepiandrosterone sulfate sulfatase; arylsulfatase C; steroid 3-sulfatase; steroid sulfate sulfohydrolase; dehydroepiandrosterone sulfatase; pregnenolone sulfatase; phenolic steroid sulfatase; 3-β-hydroxysteroid sulfate sulfatase |
| Systematic name: |
steryl-sulfate sulfohydrolase |
| Comments: |
Also acts on some related steryl sulfates. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9025-62-1 |
| References: |
| 1. |
Roy, A.B. The steroid sulphatase of Patella vlugata. Biochim. Biophys. Acta 15 (1954) 300–301. [DOI] [PMID: 13208702] |
| 2. |
Roy, A.B. The synthesis and hydrolysis of sulfate esters. Adv. Enzymol. Relat. Subj. Biochem. 22 (1960) 205–235. [PMID: 13744184] |
| 3. |
Stitch, S.R., Halkerston, I.D.K. and Hillman, J. The enzymic hydrolysis of steroid conjugates. 1. Sulphatase and β-glucuronidase activity of molluscan extracts. Biochem. J. 63 (1965) 705–710. [PMID: 13355874] |
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| [EC 3.1.6.2 created 1961] |
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