| EC |
3.1.4.4 |
| Accepted name: |
phospholipase D |
| Reaction: |
a phosphatidylcholine + H2O = choline + a phosphatidate |
| Other name(s): |
lipophosphodiesterase II; lecithinase D; choline phosphatase |
| Systematic name: |
phosphatidylcholine phosphatidohydrolase |
| Comments: |
Also acts on other phosphatidyl esters. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9001-87-0 |
| References: |
| 1. |
Astrachan, L. The bond hydrolyzed by cardiolipin-specific phospholipase D. Biochim. Biophys. Acta 296 (1973) 79–88. [DOI] [PMID: 4632675] |
| 2. |
Einset, E. and Clark, W.L. The enzymatically catalyzed release of choline from lecithin. J. Biol. Chem. 231 (1958) 703–715. [PMID: 13539005] |
| 3. |
Hanahan, D.J. and Chaikoff, I.L. On the nature of the phosphorus-containing lipides of cabbage leaves and their relation to a phospholipide-splitting enzyme contained in these leaves. J. Biol. Chem. 172 (1948) 191–198. [PMID: 18920784] |
| 4. |
Tookey, H.L. and Balls, A.K. Plant phospholipase D. I. Studies on cottonseed and cabbage phospholipase D. J. Biol. Chem. 218 (1956) 213–224. [PMID: 13278329] |
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| [EC 3.1.4.4 created 1961] |
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