EC |
3.1.3.97 |
Accepted name: |
3′,5′-nucleoside bisphosphate phosphatase |
Reaction: |
nucleoside 3′,5′-bisphosphate + H2O = nucleoside 5′-phosphate + phosphate |
Systematic name: |
nucleoside-3′,5′-bisphosphate 3′-phosphohydrolase |
Comments: |
The enzyme, characterized from the bacterium Chromobacterium violaceum, has similar catalytic efficiencies with all the bases. The enzyme has similar activity with ribonucleoside and 2′-deoxyribonucleoside 3′,5′-bisphosphates, but shows no activity with nucleoside 2′,5′-bisphosphates (cf. EC 3.1.3.7, 3′(2′),5′-bisphosphate nucleotidase). |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
References: |
1. |
Cummings, J.A., Vetting, M., Ghodge, S.V., Xu, C., Hillerich, B., Seidel, R.D., Almo, S.C. and Raushel, F.M. Prospecting for unannotated enzymes: discovery of a 3′,5′-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily. Biochemistry 53 (2014) 591–600. [DOI] [PMID: 24401123] |
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[EC 3.1.3.97 created 2015] |
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